DrugAge entry for Arbutin

Name: Arbutin
Synonyms: 4-Hydroxyphenyl beta-D-glucopyranoside • 4-Hydroxyphenyl-.beta.-D-glucopyranoside • 4-Hydroxyphenyl-beta-D-glucopyranoside • 497-76-7 • arbutin • Arbutin, 95% • Arbutine • Arbutoside • Arbutyne • beta-Arbutin • C5INA23HXF • CHEBI:18305 • CHEMBL232202 • Hydroquinone beta-D-glucopyranoside • hydroquinone O-beta-D-glucopyranoside • Hydroquinone |A-D-glucopyranoside • Hydroquinone-O-beta-D-glucopyranoside • MFCD00016915 • p-Arbutin • p-Hydroxyphenyl beta-D-glucopyranoside • p-Hydroxyphenyl beta-D-glucoside • UNII-C5INA23HXF • Ursi • Ursin • Uvasol
CAS Number: 497-76-7
IUPAC Name: (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-(4-hydroxyphenoxy)oxane-3,4,5-triol
PubChem CID
SEP-L1000 side effects: Abdominal pain, Anxiety, Asthenia, Body temperature increased, Diarrhoea, Dizziness, Dysgeusia, Dyspepsia, Dyspnoea, Erythema, Headache, Hypersensitivity, Hypotension, Insomnia, Myalgia, Nausea, Pain, Paraesthesia, Pruritus, Rash, Thrombocytopenia, Urticaria, Vomiting

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Arbutin

Average/Median Lifespan
Max Lifespan
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References

Zhou L, et al. (2017) Arbutin increases Caenorhabditis elegans longevity and stress resistance PeerJ () PubMed

DGIdb Human Drug-Gene Interactions for Arbutin

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Arbutin

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id