DrugAge entry for Anisomycin

Name: Anisomycin
Synonyms: (-)-Anisomycin • (2R,3S,4S)-2-(p-Methoxybenzyl)-3,4-pyrrolidinediol 3-acetate • (2R,3S,4S)-4-hydroxy-2-(4-methoxybenzyl)pyrrolidin-3-yl acetate • 1,4,5-Trideoxy-1,4-imino-5-(p-methoxyphenyl)-D-xylo-pentitol 3-acetate • 2-(p-Methoxybenzyl)-3,4-pyrrolidinediol 3-acetate • 22862-76-6 • 6C74YM2NGI • Anisomycin from Streptomyces griseolus • Anisomycin,streptomyces griseolus • CHEBI:338412 • Flagecidin • MFCD00077650 • MLS001066392 • NSC-76712 • NSC76712 • SMR000471874 • TCMDC-125504 • UNII-6C74YM2NGI • Upjohn 204t3 • [(2R,3S,4S)-4-hydroxy-2-[(4-methoxyphenyl)methyl]pyrrolidin-3-yl] acetate
CAS Number: 22862-76-6
IUPAC Name: [(2R,3S,4S)-4-hydroxy-2-[(4-methoxyphenyl)methyl]pyrrolidin-3-yl] acetate
PubChem CID: 253602

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Anisomycin

Average/Median Lifespan
Max Lifespan
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References

Tarkhov, AE et al. (2019) A universal transcriptomic signature of age reveals the temporal scaling of Caenorhabditis elegans aging trajectories. Sci Rep 9(1)7368 PubMed

DGIdb Human Drug-Gene Interactions for Anisomycin

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Anisomycin

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id