DrugAge entry for Alsterpaullone

Name: Alsterpaullone
Synonyms: 1q3w • 237430-03-4 • 6-hydrazinylpicolinicacid • 7,12-dihydro-9-nitro-indolo[3,2-d][1]benzazepin-6(5H)-one • 7,12-Dihydro-9-nitroindolo[3,2-d][1]benzazepin-6(5H)-one • 9-nitro-7,12-dihydro-5H-indolo[3,2-d][1]benzazepin-6-one • 9-Nitro-7,12-dihydroindolo-[3,2-d][1]benzazepin-6(5)-one • 9-Nitro-7,12-dihydroindolo[3,2-d][1]benzazepin-6(5H)-one • 9-Nitropaullone • Alsterpaullone derivative, 2 • CBiol_001723 • CHEMBL50894 • Kinome_3754 • Lopac0_000057 • MFCD02683579 • MLS002702475 • NSC 705701 • NSC-705701 • Paullone Analog 1 • S0354
CAS Number: 237430-03-4
IUPAC Name: 9-nitro-7,12-dihydro-5H-indolo[3,2-d][1]benzazepin-6-one
PubChem CID: 5005498

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for Alsterpaullone

Average/Median Lifespan
Max Lifespan
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References

Tarkhov, AE et al. (2019) A universal transcriptomic signature of age reveals the temporal scaling of Caenorhabditis elegans aging trajectories. Sci Rep 9(1)7368 PubMed

DGIdb Human Drug-Gene Interactions for Alsterpaullone

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for Alsterpaullone

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id