DrugAge entry for AZD2281

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for AZD2281

Average/Median Lifespan
Max Lifespan
Hide Charts

References

Ai Ito (2021) Metolazone upregulates mitochondrial chaperones and extends lifespan in Caenorhabditis elegans Biogerontology 22()119-131 PubMed

DGIdb Human Drug-Gene Interactions for AZD2281

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for AZD2281

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id