DrugAge entry for AEG 3482

Name: AEG 3482
Synonyms: 6-Phenylimidazo(2,1-b)-1,3,4-thiadiazole-2-sulfonamide • 6-phenylimidazo[2,1-b]-1,3,4-thiadiazole-2-sulfonamide • 6-phenylimidazo[2,1-b][1,3,4]thiadiazole-2-sulfonamide • 63735-71-7 • 7EZF1A283N • ABP000483 • AEG 3482 • AEG-3482 • AEG-3482/AEG3482/ • AEG3482 • BCP01890 • CHEBI:114182 • CHEMBL19231 • DTXSID80213176 • HMS1538B12 • HMS3269J11 • HMS3413N15 • HMS3677N15 • Imidazo(2,1-b)-1,3,4-thiadiazole-2-sulfonamide, 6-phenyl- • Imidazo[2,1-b]-1,3,4-thiadiazole-2-sulfonamide, 6-phenyl- • Oprea1_698164 • SCHEMBL2540289 • TimTec1_001442 • UNII-7EZF1A283N • ZINC75086
CAS Number
IUPAC Name: 6-phenylimidazo[2,1-b][1,3,4]thiadiazole-2-sulfonamide
PubChem CID: 698112

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for AEG 3482

Average/Median Lifespan
Max Lifespan
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References

Lombard, DB et al. (2020) High-throughput small molecule screening reveals Nrf2-dependent and -independent pathways of cellular stress resistance. Sci Adv 6(40) PubMed

DGIdb Human Drug-Gene Interactions for AEG 3482

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for AEG 3482

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id