DrugAge entry for ABL127

Name: ABL127
Synonyms: 1073529-41-5 • 4-OXO-3,3-DIPHENYL-[1,2]DIAZETIDINE-1,2-DICARBOXYLIC ACID DIMETHYL ESTER • ABL 127 • ABL-127 • ABL127, >=98% (HPLC) • BDBM75707 • CHEMBL1475741 • cid_24856225 • CS-7966 • dimethyl (3R)-3-cyclopentyl-4-oxo-3-phenyldiazetidine-1,2-dicarboxylate • GTPL8608 • HMS2221E21 • HMS3329A17 • HMS3749O17 • ML174 • MLS001250337 • SR-01000786812 • SR-01000786812-5 • YSB52941 • ZINC15924774
CAS Number
IUPAC Name: dimethyl (3R)-3-cyclopentyl-4-oxo-3-phenyldiazetidine-1,2-dicarboxylate
PubChem CID: 24856225

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for ABL127

Average/Median Lifespan
Max Lifespan
Hide Charts

References

Chen, AL et al. (2019) Pharmacological convergence reveals a lipid pathway that regulates C. elegans lifespan. Nat Chem Biol 15(5)453-462 PubMed

DGIdb Human Drug-Gene Interactions for ABL127

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for ABL127

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id