DrugAge entry for AA74-1

Name: AA74-1
Synonyms: 1-((2,5-Dichloro-4-methoxyphenyl)sulfonyl)piperidine • 1-(2,5-Dichloro-4-methoxy-benzenesulfonyl)-piperidine • 1-(2,5-dichloro-4-methoxybenzenesulfonyl)piperidine • 1-(2,5-dichloro-4-methoxyphenyl)sulfonylpiperidine • 1-(2,5-dichloro-4-methoxyphenylsulfonyl)piperidine • 1361532-00-4 • 2,5-dichloro-4-methoxy-1-(piperidylsulfonyl)benzene • 433690-62-1 • AA 41612 • AA-41612 • AA41612 • AKOS001273945 • AP-263/40917840 • Cambridge id 6964506 • EX-A4858 • MCULE-5698868417 • Oprea1_771695 • SCHEMBL17008468 • ST50172259 • ZINC5675319
CAS Number
IUPAC Name: 1-(2,5-dichloro-4-methoxyphenyl)sulfonylpiperidine
PubChem CID: 4528045

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for AA74-1

Average/Median Lifespan
Max Lifespan
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References

Chen, AL et al. (2019) Pharmacological convergence reveals a lipid pathway that regulates C. elegans lifespan. Nat Chem Biol 15(5)453-462 PubMed

DGIdb Human Drug-Gene Interactions for AA74-1

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for AA74-1

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id