DrugAge entry for 7,8-Dihydroxyflavone

Name: 7,8-Dihydroxyflavone
Synonyms: 38183-03-8 • 4H-1-Benzopyran-4-one, 7,8-dihydroxy-2-phenyl- • 7,8-DHF • 7,8-Dihydroxy-2-phenyl-4-benzopyrone • 7,8-Dihydroxy-2-phenyl-4H-1-benzopyran-4-one • 7,8-dihydroxy-2-phenyl-4H-chromen-4-one • 7,8-Dihydroxy-2-phenyl-chromen-4-one • 7,8-dihydroxy-2-phenylchromen-4-one • 7,8-Dihydroxy-flavone • 7,8-dihydroxyflavone • 7,8-Dihydroxyflavone hydrate • 7,8-diOH-Flavone • ACMC-1AFU3 • ADB6MA8ZV2 • BRN 0234350 • CHEMBL75267 • EINECS 253-812-4 • MFCD00006836 • PubChem9845 • Spectrum2_000952 • Spectrum3_000213 • Spectrum4_001823 • Spectrum5_000585 • Spectrum_001087 • UNII-ADB6MA8ZV2
CAS Number: 38183-03-8
IUPAC Name: 7,8-dihydroxy-2-phenylchromen-4-one
PubChem CID: 1880

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for 7,8-Dihydroxyflavone

Average/Median Lifespan
Max Lifespan
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References

Guerrero-Rubio, MA et al. (2021) Flavonoids' Effects on Antioxidants (Basel) 10(3) PubMed

DGIdb Human Drug-Gene Interactions for 7,8-Dihydroxyflavone

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for 7,8-Dihydroxyflavone

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id