DrugAge entry for 3-methylxanthine

Name: 3-methylxanthine
Synonyms: 1076-22-8 • 1H-Purine-2,6-dione, 3,7-dihydro-3-methyl- • 2,6-Dihydroxy-3-methylpurine • 3 MX • 3,7-Dihydro-3-methyl-1H-purine-2,6-dione • 3-METHYL XANTHINE • 3-methyl-1,3-dihydropurine-2,6-dione • 3-Methyl-1H-purine-2,6(3H,7H)-dione • 3-methyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione • 3-Methyl-3,9-dihydro-1H-purine-2,6-dione • 3-Methyl-3,9-dihydro-purine-2,6-dione • 3-methyl-7H-purine-2,6-dione • 3-methyl-7H-xanthine • 3-Methylxanthine • 3-Methylxanthine, 97% • CCRIS 5817 • CHEBI:62207 • CHEMBL619 • EINECS 214-058-1 • GMSNIKWWOQHZGF-UHFFFAOYSA-N • MFCD00005580 • NSC 515466 • UNII-WS6X982OEC • WS6X982OEC • Xanthine, 3-methyl-
CAS Number: 1076-22-8
IUPAC Name: 3-methyl Xanthine
PubChem CID

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for 3-methylxanthine

Average/Median Lifespan
Max Lifespan
Hide Charts

References

Du X, et al. (2018) Low Concentrations of Caffeine and Its Analogs Extend the Lifespan of Caenorhabditis elegans by Modulating IGF-1-Like Pathway Frontiers in ageing neuroscience () PubMed

DGIdb Human Drug-Gene Interactions for 3-methylxanthine

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for 3-methylxanthine

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id