DrugAge entry for 3-Morpholinosydnonimine hydrochloride

Name: 3-Morpholinosydnonimine hydrochloride
Synonyms: (3-Morpholino-1,2,3-oxadiazol-3-ium-5-yl)amide hydrochloride • 3-(4-Morpholinyl)sydnone imine hydrochloride • 3-(4-Morpholinyl)Sydnonimine HCl • 3-morpholin-4-yl-1-oxa-3-azonia-2-azanidacyclopent-3-en-5-imine;hydrochloride • 3-morpholino-sydnonimine hydrochloride • 3-Morpholino-sydnoniminehydrochloride • 3-Morpholinosydnoimine hydrochloride • 3-Morpholinosydnoneimine HCl • 3-Morpholinosydnonimine HCl • 3-morpholinosydnonimine hydro-chloride • 3-Morpholinosydnonimine hydrochloride • 5-AMINO-3-(4-MORPHOLINYL)-1,2,3-OXADIAZOLIUM CHLORIDE • AKOS022181148 • AKOS025213271 • CHEMBL538104 • MFCD00214332 • MLS000028691 • MLS000860006 • Molsidomine Impurity A • Opera_ID_1704 • SCHEMBL960238 • sin-1 • SIN-1, Hydrochloride • SMR000058925 • Tox21_500247 • Tox21_500854
CAS Number
IUPAC Name: 3-morpholin-4-yl-1-oxa-3-azonia-2-azanidacyclopent-3-en-5-imine;hydrochloride
PubChem CID: 9859122

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for 3-Morpholinosydnonimine hydrochloride

Average/Median Lifespan
Max Lifespan
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References

Lombard, DB et al. (2020) High-throughput small molecule screening reveals Nrf2-dependent and -independent pathways of cellular stress resistance. Sci Adv 6(40) PubMed

DGIdb Human Drug-Gene Interactions for 3-Morpholinosydnonimine hydrochloride

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for 3-Morpholinosydnonimine hydrochloride

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id