DrugAge entry for 17-dimethylaminoethylamino-17-demethoxygeldanamycin hydrochloride

Name: 17-dimethylaminoethylamino-17-demethoxygeldanamycin hydrochloride
Synonyms: DMAG
CAS Number
IUPAC Name
PubChem CID: 5288674

Summary

Species	No. Entries	MAX(Avg/Med Lifespan Change %)	MEAN(Avg/Med Lifespan Change %)	MAX(Max Lifespan Change %)	MEAN(Max Lifespan Change %)

Results

Compound/Formulation	Species	Sex	Strain	Dosage	Avg/Med Lifespan Change (%)	Avg/Med Lifespan Significance	Max Lifespan Change (%)	Reference

Lifespan Charts for 17-dimethylaminoethylamino-17-demethoxygeldanamycin hydrochloride

Average/Median Lifespan
Max Lifespan
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References

Strong, R et al. (2020) Rapamycin-mediated mouse lifespan extension: Late-life dosage regimes with sex-specific effects. Aging cell 19(11)e13269 PubMed

DGIdb Human Drug-Gene Interactions for 17-dimethylaminoethylamino-17-demethoxygeldanamycin hydrochloride

Interaction Types	Gene Symbol	Common Name	HGNC Id	DGIdb Sources	References

Stitch DB Human Drug-Protein Interactions for 17-dimethylaminoethylamino-17-demethoxygeldanamycin hydrochloride

Up to 20 direct protein and drug interactions are displayed, having a medium confidence score (0.450) or above. Second order interactions are tabulated below.

Ensembl Id	StringDB Id