Saccharomyces cerevisiae GenDR Dietary Restriction Gene Manipulation: ATG5

Gene Information (Entrez Gene ID: 855954)

Symbol
ATG5
Aliases
APG5
Name
Atg5p
Organism
Saccharomyces cerevisiae (AnAge)
Entrez Gene ID
855954

Potential relevance to dietary restriction and ageing

Observations

Methionine restriction (a form of dietary restriction), aquired through MET2 or MET17 knockout, enhances lifespan in yeast. In both MET2 and MET17 models, this lifespan extension is abolished by the deletion of ATG5, ATG7, or ATG8 lifespan reaching comparable or even lower survival levels to those of controls.

References

    In other databases

    GenAge model organism genes
    • This gene is present as ATG5
    • A homolog of this gene for Mus musculus is present as Atg5

    Homologs

    Danio rerio
    atg5
    Drosophila melanogaster
    Atg5
    Homo sapiens
    ATG5
    Mus musculus
    Atg5
    Rattus norvegicus
    Atg5
    Schizosaccharomyces pombe
    atg5

    External links

    Saccharomyces Genome Database
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    Ensembl
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    Entrez Gene
    ID 855954
    Homologues
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    UniProt
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    Internet
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