LongevityMap variant
- Longevity Association
- Non-significant
- Population
- Dutch
- Study Design
- -493G/T and Q95H allele and haplotype frequencies were examined in 379 nonagenarians, 525 of their offspring, and 251 partners of their offspring and in 655 octogenarians and 244 young controls
- Conclusions
- No association with longevity was found
- HGNC symbol
- MTTP
- Aliases
- ABL; MTP
- Common name
- microsomal triglyceride transfer protein
- Description
- MTP encodes the large subunit of the heterodimeric microsomal triglyceride transfer protein. Protein disulfide isomerase (PDI) completes the heterodimeric microsomal triglyceride transfer protein, which has been shown to play a central role in lipoprotein assembly. Mutations in MTP can cause abetalipoproteinemia. [provided by RefSeq, Jul 2008]
- Other longevity studies of this gene
- 20
- OMIM
- 157147
- Ensembl
- ENSG00000138823
- UniProt/Swiss-Prot
- B7Z7X3_HUMAN
- Entrez Gene
- 4547
- UniGene
- 195799
- HapMap
- View on HapMap
Homologs in model organisms
- Danio rerio
- mtp
- Drosophila melanogaster
- Mtp
- Mus musculus
- Mttp
- Rattus norvegicus
- Mttp
Beekman et al. (2006)
Other variants which are also part of this study