Protein sequence for HAGRID 243 (MLH1) for HAGRID 243 (MLH1)

Gene information

HGNC symbolMLH1
Common namemutL homolog 1

GO protein functions

GO:0003682chromatin binding
GO:0003697single-stranded DNA binding
GO:0005515protein binding
GO:0005515protein binding
GO:0005524ATP binding
GO:0016887ATPase activity
GO:0032137guanine/thymine mispair binding
GO:0032407MutSalpha complex binding

Protein sequence for HAGRID 243 (MLH1)

Protein sequence for HAGRID 243 (MLH1) source (RefSeq)NP_000240
Sequence length756 aa

Sequence

     1  MSFVAGVIRR LDETVVNRIA AGEVIQRPAN AIKEMIENCL DAKSTSIQVI VKEGGLKLIQ
    61  IQDNGTGIRK EDLDIVCERF TTSKLQSFED LASISTYGFR GEALASISHV AHVTITTKTA
   121  DGKCAYRASY SDGKLKAPPK PCAGNQGTQI TVEDLFYNIA TRRKALKNPS EEYGKILEVV
   181  GRYSVHNAGI SFSVKKQGET VADVRTLPNA STVDNIRSIF GNAVSRELIE IGCEDKTLAF
   241  KMNGYISNAN YSVKKCIFLL FINHRLVEST SLRKAIETVY AAYLPKNTHP FLYLSLEISP
   301  QNVDVNVHPT KHEVHFLHEE SILERVQQHI ESKLLGSNSS RMYFTQTLLP GLAGPSGEMV
   361  KSTTSLTSSS TSGSSDKVYA HQMVRTDSRE QKLDAFLQPL SKPLSSQPQA IVTEDKTDIS
   421  SGRARQQDEE MLELPAPAEV AAKNQSLEGD TTKGTSEMSE KRGPTSSNPR KRHREDSDVE
   481  MVEDDSRKEM TAACTPRRRI INLTSVLSLQ EEINEQGHEV LREMLHNHSF VGCVNPQWAL
   541  AQHQTKLYLL NTTKLSEELF YQILIYDFAN FGVLRLSEPA PLFDLAMLAL DSPESGWTEE
   601  DGPKEGLAEY IVEFLKKKAE MLADYFSLEI DEEGNLIGLP LLIDNYVPPL EGLPIFILRL
   661  ATEVNWDEEK ECFESLSKEC AMFYSIRKQY ISEESTLSGQ QSEVPGSIPN SWKWTVEHIV
   721  YKALRSHILP PKHFTEDGNI LQLANLPDLY KVFERC
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