Protein sequence for HAGRID 237 (GCLC) for HAGRID 237 (GCLC)

Gene information

HGNC symbolGCLC
Common nameglutamate-cysteine ligase, catalytic subunit

GO protein functions

GO:0000287magnesium ion binding
GO:0004357glutamate-cysteine ligase activity
GO:0004357glutamate-cysteine ligase activity
GO:0005524ATP binding
GO:0016595glutamate binding
GO:0043531ADP binding
GO:0046982protein heterodimerization activity
GO:0050662coenzyme binding

Protein sequence for HAGRID 237 (GCLC)

Protein sequence for HAGRID 237 (GCLC) source (RefSeq)NP_001489
Sequence length637 aa

Sequence

     1  MGLLSQGSPL SWEETKRHAD HVRRHGILQF LHIYHAVKDR HKDVLKWGDE VEYMLVSFDH
    61  ENKKVRLVLS GEKVLETLQE KGERTNPNHP TLWRPEYGSY MIEGTPGQPY GGTMSEFNTV
   121  EANMRKRRKE ATSILEENQA LCTITSFPRL GCPGFTLPEV KPNPVEGGAS KSLFFPDEAI
   181  NKHPRFSTLT RNIRHRRGEK VVINVPIFKD KNTPSPFIET FTEDDEASRA SKPDHIYMDA
   241  MGFGMGNCCL QVTFQACSIS EARYLYDQLA TICPIVMALS AASPFYRGYV SDIDCRWGVI
   301  SASVDDRTRE ERGLEPLKNN NYRISKSRYD SIDSYLSKCG EKYNDIDLTI DKEIYEQLLQ
   361  EGIDHLLAQH VAHLFIRDPL TLFEEKIHLD DANESDHFEN IQSTNWQTMR FKPPPPNSDI
   421  GWRVEFRPME VQLTDFENSA YVVFVVLLTR VILSYKLDFL IPLSKVDENM KVAQKRDAVL
   481  QGMFYFRKDI CKGGNAVVDG CGKAQNSTEL AAEEYTLMSI DTIINGKEGV FPGLIPILNS
   541  YLENMEVDVD TRCSILNYLK LIKKRASGEL MTVARWMREF IANHPDYKQD SVITDEMNYS
   601  LILKCNQIAN ELCECPELLG SAFRKVKYSG SKTDSSN
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