- Symbol
- UCP2
- Aliases
- UCPH; BMIQ4; SLC25A8
- Name
- uncoupling protein 2 (mitochondrial, proton carrier)
- Organism
- Drosophila melanogaster (AnAge)
- Observations
- Overexpression of human UCP2 in the fly nervous system extended lifespan by 10-30%. Ubiquitous overexpression was lethal.
- % change in avg or median lifespan
- Lifespan is 10-30% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Overexpression
- Longevity Category
- Pro-Longevity
- Primary reference
-
- GenAge model organism genes
- A homolog of this gene for Mus musculus is present as Ucp2
- GenAge human genes
- A homolog of this gene for Homo sapiens is present as UCP2
- GenDR gene manipulations
- A homolog of this gene for Caenorhabditis elegans is present as ucp2
- LongevityMap
- A homolog of this gene for Homo sapiens is present as UCP2
- Homo sapiens
- UCP2
- Homo sapiens
- UCP2
- Homo sapiens
- UCP2
- Homo sapiens
- UCP2
- FlyBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (7351)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for UCP2 (Drosophila melanogaster)