Drosophila melanogasterGenAge entry for mys (Drosophila melanogaster)

Gene information (ID: 451)

Symbol
mys
Aliases
beta-int; beta-Int; beta-integrin; beta-PS; beta1; beta
Name
myospheroid
Organism
Drosophila melanogaster (AnAge)
Known functions and activities
Beta integrin

Potential relevance to longevity and/or ageing

Observations
Heterozygous MYS (beta-integrin) female mutants display extended median and maximum lifespan.
% change in avg or median lifespan
Female median lifespan is 44-95% higher.
Lifespan Effect
Increase
Genetic Manipulation
Mutation
Longevity Category
Anti-Longevity
Primary reference
    Observations
    Mutants exhibit ameliorated age-related declines in locomotor activity and an increase in mean lifespan of 20%.
    % change in avg or median lifespan
    Average female lifespan is 20% higher.
    Lifespan Effect
    Increase
    Genetic Manipulation
    Mutation
    Longevity Category
    Anti-Longevity
    Primary reference

      In other databases

      GenAge model organism genes
      • A homolog of this gene for Caenorhabditis elegans is present as pat-3

      Homologs in other organisms

      Caenorhabditis elegans
      pat-3
      Danio rerio
      itgbl1
      Danio rerio
      itgb1b.2
      Danio rerio
      itgb1a
      Danio rerio
      itgb2
      Danio rerio
      itgb7
      Danio rerio
      itgb1b.1
      Danio rerio
      CABZ01058720.1
      Homo sapiens
      ITGB7
      Homo sapiens
      ITGB2
      Homo sapiens
      ITGB1
      Homo sapiens
      ITGBL1
      Mus musculus
      Itgbl1
      Mus musculus
      Itgb1
      Mus musculus
      Itgb2l
      Mus musculus
      Itgb7
      Mus musculus
      Itgb2
      Rattus norvegicus
      Itgbl1
      Rattus norvegicus
      Itgb2
      Rattus norvegicus
      Itgb7
      Rattus norvegicus
      Itgb1

      External links

      FlyBase
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      Ensembl
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      Entrez Gene
      View on Entrez Gene database (44885)
      Homologues
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      UniProt
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      Internet
      Search Google or Search Google Scholar