- Symbol
- Trpv1
- Name
- transient receptor potential cation channel, subfamily V, member 1
- Organism
- Mus musculus (AnAge)
- Observations
- Mice lacking TRPV1 pain receptors are long-lived and display a young metabolic profile at old age. Both median and maximum lifespan are extended. Longevity is extended in both genders, with 11.9% increase in male mutants and 15.9% in females.
- % change in avg or median lifespan
- Male median lifespan is 11.9% higher; female median lifespan is 15.9% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Mutation
- Longevity Category
- Anti-Longevity
- Primary reference
-
- GenAge model organism genes
- A homolog of this gene for Caenorhabditis elegans is present as ocr-2
- GenAge human genes
- A homolog of this gene for Homo sapiens is present as TRPV1
- Caenorhabditis elegans
- ocr-1
- Caenorhabditis elegans
- ocr-2
- Caenorhabditis elegans
- ocr-3
- Caenorhabditis elegans
- ocr-4
- Caenorhabditis elegans
- osm-9
- Danio rerio
- trpv1
- Drosophila melanogaster
- iav
- Drosophila melanogaster
- nan
- Homo sapiens
- TRPV1
- Rattus norvegicus
- Trpv1
- Mouse Genome Informatics
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (193034)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for Trpv1 (Mus musculus)