Drosophila melanogasterGenAge entry for Mad (Drosophila melanogaster)

Gene information (ID: 1903)

Symbol
Mad
Name
Mothers against dpp
Organism
Drosophila melanogaster (AnAge)

Potential relevance to longevity and/or ageing

Observations
Post developmental RNA interference of Mad decreases lifespan.
% change in avg or median lifespan
Mean lifespan is 22.2% lower.
Lifespan Effect
Decrease
Genetic Manipulation
Post developmental RNA interference
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Caenorhabditis elegans is present as daf-8
    CellAge
    • A homolog of this gene for Homo sapiens is present as SMAD1
    • A homolog of this gene for Homo sapiens is present as SMAD5

    Homologs in other organisms

    Caenorhabditis elegans
    daf-8
    Caenorhabditis elegans
    sma-2
    Caenorhabditis elegans
    sma-3
    Danio rerio
    smad5
    Danio rerio
    smad9
    Danio rerio
    smad1
    Homo sapiens
    SMAD5
    Homo sapiens
    SMAD1
    Homo sapiens
    SMAD9
    Mus musculus
    Smad1
    Mus musculus
    Smad5
    Mus musculus
    Smad9
    Rattus norvegicus
    Smad9
    Rattus norvegicus
    Smad9
    Rattus norvegicus
    LOC103691556
    Rattus norvegicus
    Smad5
    Rattus norvegicus
    Smad1

    External links

    FlyBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (33529)
    Homologues
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    UniProt
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    Internet
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