- Symbol
- Mrp4
- Name
- Multidrug resistance protein 4 ortholog
- Organism
- Drosophila melanogaster (AnAge)
- Observations
- Compared to wild-type controls, dMRP4 mutant flies have a much shorter mean lifespan (by about 47%) and a decreased in maximum lifespan (by 24%).
- % change in max lifespan
- Maximum lifespan is 24% lower.
- % change in avg or median lifespan
- Mean lifespan is 47% lower.
- Lifespan Effect
- Decrease
- Genetic Manipulation
- Mutation
- Longevity Category
- Pro-Longevity
- Primary reference
-
- Observations
- Flies overexpressing dMRP4 have an increased mean lifespan of up to 16% and an increased maximum lifespan of up to 8%.
- % change in max lifespan
- Maximum lifespan is up to 8% higher.
- % change in avg or median lifespan
- Mean lifespan is up to 16% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Overexpression
- Longevity Category
- Pro-Longevity
- Primary reference
-
- LongevityMap
- A homolog of this gene for Homo sapiens is present as ABCC4
- Danio rerio
- abcc4
- Homo sapiens
- ABCC4
- Mus musculus
- Abcc4
- Rattus norvegicus
- Abcc4
- Saccharomyces cerevisiae
- YCF1
- FlyBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (41387)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for Mrp4 (Drosophila melanogaster)