- Symbol
- zfh-2
- Name
- Protein ZFH-2
- Organism
- Caenorhabditis elegans (AnAge)
- Observations
- Several of the RNAi candidates (dve-1; lin-40; nhr-49; ceh-20; lin-11; and nhr-77) appeared to non-discriminately shorten lifespan in all strains tested, suggesting that the corresponding transcription factors are broadly required for survival. Interestingly, four RNAi clones (ZC123.3; nhr-119; ceh-37; and aha-1) affected wild-type and isp-1;ctb-1 mutant worms' lifespan to the same extent but exerted only a moderate or no effect on daf-16 and age-1 mutant longevity.
- % change in avg or median lifespan
- Average lifespan is 45% lower.
- Lifespan Effect
- Decrease
- Genetic Manipulation
- RNA interference
- Longevity Category
- Pro-Longevity
- Primary reference
-
- CellAge gene expression
- A homolog of this gene for Homo sapiens is present as ZFHX4
- Danio rerio
- si:ch73-386h18.1
- Danio rerio
- zfhx4
- Danio rerio
- zfhx3
- Drosophila melanogaster
- zfh2
- Homo sapiens
- ZFHX4
- Homo sapiens
- ZFHX3
- Homo sapiens
- ZFHX2
- Mus musculus
- Zfhx2
- Mus musculus
- Zfhx3
- Mus musculus
- Zfhx4
- Rattus norvegicus
- Zfhx4
- Rattus norvegicus
- Zfhx2
- Rattus norvegicus
- Zfhx3
- WormBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (171670)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for zfh-2 (Caenorhabditis elegans)