Caenorhabditis elegansGenAge entry for tlf-1 (Caenorhabditis elegans)

Gene information (ID: 675)

Symbol
tlf-1
Name
TBP-Like Factor
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Transcription factor

Potential relevance to longevity and/or ageing

Observations
RNA interference decreased median lifespan by 33% in wild type animals and 49% in daf-2 mutants.
% change in avg or median lifespan
Median lifespan is 33% lower.
Lifespan Effect
Decrease
Genetic Manipulation
RNA interference
Longevity Category
Pro-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    tbpl1
    Drosophila melanogaster
    Trf2
    Homo sapiens
    TBPL1
    Mus musculus
    Tbpl1
    Rattus norvegicus
    Tbpl1
    Saccharomyces cerevisiae
    SPT15

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (172676)
    Homologues
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    UniProt
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    Internet
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