Caenorhabditis elegansGenAge entry for mvk-1 (Caenorhabditis elegans)

Gene information (ID: 746)

Symbol
mvk-1
Name
Y42G9A.4b
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Mevalonate kinase

Potential relevance to longevity and/or ageing

Observations
RNA interference decreased median lifespan by 14% in wild type animals and 33% in daf-2 mutants.
% change in avg or median lifespan
Median lifespan is 14% lower.
Lifespan Effect
Decrease
Genetic Manipulation
RNA interference
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    CellAge
    • A homolog of this gene for Homo sapiens is present as MVK

    Homologs in other organisms

    Danio rerio
    mvk
    Drosophila melanogaster
    CG33671
    Homo sapiens
    MVK
    Mus musculus
    Mvk
    Rattus norvegicus
    Mvk
    Saccharomyces cerevisiae
    ERG12

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (175863)
    Homologues
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    UniProt
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    Internet
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