Caenorhabditis elegansGenAge entry for mkk-4 (Caenorhabditis elegans)

Gene information (ID: 437)

Symbol
mkk-4
Name
MKK (MAP Kinase Kinase) homolog
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
MAP kinase kinase homologue

Potential relevance to longevity and/or ageing

Observations
Mutation reduced maximum lifespan 23%.
% change in max lifespan
Maximum lifespan is 23% lower.
Lifespan Effect
Decrease
Genetic Manipulation
Mutation
Longevity Category
Anti-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    map2k4b
    Danio rerio
    map2k4a
    Drosophila melanogaster
    Mkk4
    Homo sapiens
    MAP2K4
    Mus musculus
    Map2k4
    Rattus norvegicus
    Map2k4
    Saccharomyces cerevisiae
    PBS2

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (185682)
    Homologues
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    UniProt
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    Internet
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