GenAge entry for mir-80 (Caenorhabditis elegans)
Gene information (ID: 2175)
- Symbol
- mir-80
- Name
- microRNA-80
- Organism
- Caenorhabditis elegans (AnAge)
Potential relevance to longevity and/or ageing
- Observations
- Deletion of mir-80 in worms resulted in increased lifespan and healthspan compared to wild type worms. Average age at 75% mortality was increased by 24%. Pharyngeal pumping rates were maintained significantly later into life. Locomotory ageing was also delayed without altering behaviour. These effects were exerted via a dietary restriction mechanism.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Deletion
- Longevity Category
- Anti-Longevity
- Primary reference
-
Homologs in other organisms
No homologs found
External links
- WormBase
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- Ensembl
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- Entrez Gene
- View on Entrez Gene database (3565575)
- Homologues
- Search HomoloGene
- UniProt
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- Internet
- Search Google or Search Google Scholar