GenAge entry for mics-1 (Caenorhabditis elegans)
Gene information (ID: 2011)
- Symbol
- mics-1
- Name
- MItoChondrial Scaffolding protei
- Organism
- Caenorhabditis elegans (AnAge)
Potential relevance to longevity and/or ageing
- Observations
- RNA interference (or mutations) of mics-1 results in mutants with enhanced longevity when compated to HT115 wild-type controls (mean lifespan up to 54% higher). Additionally, termal stress of mics-1 mutants display lower reactive oxygen species production.
- % change in avg or median lifespan
- Mean lifespan is 54% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- RNA interference
- Longevity Category
- Anti-Longevity
- Primary reference
-
Homologs in other organisms
No homologs found
External links
- WormBase
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- Ensembl
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- Entrez Gene
- View on Entrez Gene database (179475)
- Homologues
- Search HomoloGene
- UniProt
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- Internet
- Search Google or Search Google Scholar