- Symbol
- mcm-2
- Name
- yeast MCM (licensing factor) related
- Organism
- Caenorhabditis elegans (AnAge)
- Known functions and activities
- Chromatin modificatioon
- Observations
- RNA interference in adulthood resulted in a 15% mean lifespan extension.
- % change in avg or median lifespan
- Average lifespan is 15% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- RNA interference
- Longevity Category
- Anti-Longevity
- Primary reference
-
- Observations
- RNAi let to a 33% decrease in median lifespan in daf-2 background and a 14% decrease in lifespan in a wild-type background.
- % change in avg or median lifespan
- Median lifespan is 14% lower.
- Lifespan Effect
- Decrease
- Genetic Manipulation
- RNA interference
- Longevity Category
- Pro-Longevity
- Primary reference
-
- GenAge model organism genes
- A homolog of this gene for Mus musculus is present as Mcm2
- CellAge gene expression
- A homolog of this gene for Homo sapiens is present as MCM2
- Danio rerio
- mcm2
- Drosophila melanogaster
- Mcm2
- Homo sapiens
- MCM2
- Mus musculus
- Mcm2
- Rattus norvegicus
- Mcm2
- Saccharomyces cerevisiae
- MCM2
- Schizosaccharomyces pombe
- mcm2
- WormBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (174841)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for mcm-2 (Caenorhabditis elegans)