Caenorhabditis elegansGenAge entry for let-765 (Caenorhabditis elegans)

Gene information (ID: 473)

Symbol
let-765
Name
LEThal
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Notch signalling pathway

Potential relevance to longevity and/or ageing

Observations
RNA interference decreased median lifespan by 27% in wild type animals, 38% in a daf-2 background and 22% in daf-2/daf-16 double mutants.
% change in avg or median lifespan
Median lifespan is 27% lower.
Lifespan Effect
Decrease
Genetic Manipulation
RNA interference
Longevity Category
Pro-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    SBNO2 (1 of many)
    Danio rerio
    sbno1
    Danio rerio
    sbno2a
    Drosophila melanogaster
    CG3491
    Drosophila melanogaster
    sno
    Homo sapiens
    SBNO2
    Homo sapiens
    SBNO1
    Mus musculus
    Sbno1
    Mus musculus
    Sbno2
    Rattus norvegicus
    Sbno2
    Rattus norvegicus
    Sbno1

    External links

    WormBase
    Search
    Ensembl
    Search
    Entrez Gene
    View on Entrez Gene database (175934)
    Homologues
    Search HomoloGene
    UniProt
    Search
    Internet
    Search Google or Search Google Scholar