Caenorhabditis elegansGenAge entry for let-418 (Caenorhabditis elegans)

Gene information (ID: 1906)

Symbol
let-418
Name
Protein let-418
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
LET-418 worm mutants (loss-of-function mutation) display an increased lifespan and stress resistance to stress in a daf-16-dependent manner.
% change in avg or median lifespan
Lifespan is up to 25% higher.
Lifespan Effect
Increase
Genetic Manipulation
Mutation
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Saccharomyces cerevisiae is present as CHD1
    CellAge
    • A homolog of this gene for Homo sapiens is present as CHD5

    Homologs in other organisms

    Danio rerio
    chd5
    Danio rerio
    chd4a
    Danio rerio
    chd4b
    Danio rerio
    chd3
    Drosophila melanogaster
    Mi-2
    Drosophila melanogaster
    Chd3
    Homo sapiens
    CHD4
    Homo sapiens
    CHD3
    Homo sapiens
    CHD5
    Mus musculus
    Chd3
    Mus musculus
    Chd4
    Mus musculus
    Chd5
    Rattus norvegicus
    Chd4
    Rattus norvegicus
    Chd5
    Rattus norvegicus
    Chd3
    Saccharomyces cerevisiae
    CHD1
    Schizosaccharomyces pombe
    mit1

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (178970)
    Homologues
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    UniProt
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    Internet
    Search Google or Search Google Scholar