- Symbol
- klf-1
- Name
- Kruppel-Like Factor (zinc finger protein)
- Organism
- Caenorhabditis elegans (AnAge)
- Observations
- Ectopic expression of klf-1 in worms, performed in a transgenic line carrying an intestine-specific construct and resulting in a modest level of overexpression, extends lifespan by approximately 15%. This effect is wwp-1 dependent.
- % change in avg or median lifespan
- Lifespan is 15% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Overexpression
- Longevity Category
- Pro-Longevity
- Primary reference
-
- GenAge model organism genes
- A homolog of this gene for Saccharomyces cerevisiae is present as SWI5
- GenDR gene manipulations
- This gene is present as klf-1
- Saccharomyces cerevisiae
- SWI5
- Saccharomyces cerevisiae
- ACE2
- WormBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (175404)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for klf-1 (Caenorhabditis elegans)