Caenorhabditis elegansGenAge entry for jmjd-2 (Caenorhabditis elegans)

Gene information (ID: 2058)

Symbol
jmjd-2
Name
Lysine-specific demethylase 4
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
RNA inteference of jmjd-2 results in an incrased lifespan of up to 13%, depending on temperature.
% change in avg or median lifespan
Mean lifespan is 13% higher.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Saccharomyces cerevisiae is present as GIS1
    GenDR gene manipulations
    • A homolog of this gene for Saccharomyces cerevisiae is present as GIS1
    CellAge
    • A homolog of this gene for Homo sapiens is present as KDM4A

    Homologs in other organisms

    Danio rerio
    kdm4aa
    Danio rerio
    kdm4ab
    Danio rerio
    kdm4c
    Drosophila melanogaster
    Kdm4B
    Drosophila melanogaster
    Kdm4A
    Homo sapiens
    KDM4C
    Homo sapiens
    KDM4A
    Mus musculus
    Kdm4a
    Mus musculus
    Kdm4c
    Rattus norvegicus
    Kdm4c
    Rattus norvegicus
    Kdm4a
    Saccharomyces cerevisiae
    GIS1
    Saccharomyces cerevisiae
    RPH1

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (175080)
    Homologues
    Search HomoloGene
    UniProt
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    Internet
    Search Google or Search Google Scholar