- Symbol
- ifta-2
- Name
- IntraFlagellar Transport Associated
- Organism
- Caenorhabditis elegans (AnAge)
- Known functions and activities
- Ciliar protein
- Observations
- Knockouts have an extended lifespan phenotype (40-50%) and are defective in dauer formation due to defects in daf-2 receptor signalling pathway in ciliatedsensory neurons. There was no additive effect of the ifta-2 mutation on the daf-2 longevity phenotype.
- % change in avg or median lifespan
- Lifespan is 40-50% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Knockout
- Longevity Category
- Anti-Longevity
- Primary reference
-
- Danio rerio
- ift22
- Homo sapiens
- IFT22
- Mus musculus
- Ift22
- Rattus norvegicus
- Ift22
- WormBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (189055)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar
GenAge entry for ifta-2 (Caenorhabditis elegans)