Caenorhabditis elegansGenAge entry for ife-1 (Caenorhabditis elegans)

Gene information (ID: 359)

Symbol
ife-1
Name
Initiation Factor 4E (eIF4E) family
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
A scaffold protein for translation initiation factors

Potential relevance to longevity and/or ageing

Observations
RNA interference increased maximum lifespan by 7-10%.
% change in max lifespan
Maximum lifespan is 7-10% higher.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference

    In other databases

    LongevityMap
    • A homolog of this gene for Homo sapiens is present as EIF4E

    Homologs in other organisms

    Danio rerio
    eif4e1b
    Danio rerio
    eif4ea
    Danio rerio
    eif4eb
    Danio rerio
    eif4e1c
    Drosophila melanogaster
    eIF4E-6
    Drosophila melanogaster
    eIF-4E
    Drosophila melanogaster
    eIF4E-3
    Drosophila melanogaster
    eIF4E-7
    Drosophila melanogaster
    eIF4E-5
    Drosophila melanogaster
    eIF4E-4
    Homo sapiens
    EIF4E1B
    Homo sapiens
    EIF4E
    Mus musculus
    Eif4e1b
    Mus musculus
    Eif4e
    Rattus norvegicus
    Eif4e
    Saccharomyces cerevisiae
    CDC33

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (176755)
    Homologues
    Search HomoloGene
    UniProt
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    Internet
    Search Google or Search Google Scholar