Caenorhabditis elegansGenAge entry for hsp-16.1 (Caenorhabditis elegans)

Gene information (ID: 342)

Symbol
hsp-16.1
Name
Heat Shock Protein
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Stress-induced chaperone

Potential relevance to longevity and/or ageing

Observations
RNA interference of hsp-16.1 in worms results in decreased lifespan (mean lifespan is 16% shorter).
% change in avg or median lifespan
Mean lifespan is 16% lower.
Lifespan Effect
Decrease
Genetic Manipulation
RNA interference
Longevity Category
Pro-Longevity
Primary reference
    Observations
    Overexpression enhanced stress resistance and extended lifespan.
    Lifespan Effect
    Increase
    Genetic Manipulation
    Overexpression
    Longevity Category
    Pro-Longevity
    Primary reference

      In other databases

      GenAge model organism genes
      • A homolog of this gene for Drosophila melanogaster is present as Hsp26
      • A homolog of this gene for Drosophila melanogaster is present as Hsp27
      • A homolog of this gene for Drosophila melanogaster is present as Hsp22
      • A homolog of this gene for Drosophila melanogaster is present as Hsp67Bc
      GenAge microarray genes
      • A homolog of this gene for Homo sapiens is present as CRYAB
      CellAge gene expression
      • A homolog of this gene for Homo sapiens is present as CRYAB

      Homologs in other organisms

      Danio rerio
      cryaba
      Danio rerio
      cryaa
      Danio rerio
      cryabb
      Danio rerio
      cryaba
      Danio rerio
      cryabb
      Danio rerio
      hspb6
      Danio rerio
      hspb6
      Danio rerio
      cryaa
      Drosophila melanogaster
      Hsp23
      Drosophila melanogaster
      Hsp26
      Drosophila melanogaster
      Hsp23
      Drosophila melanogaster
      Hsp67Ba
      Drosophila melanogaster
      Hsp27
      Drosophila melanogaster
      Hsp26
      Drosophila melanogaster
      Hsp22
      Drosophila melanogaster
      Hsp22
      Drosophila melanogaster
      Hsp27
      Drosophila melanogaster
      Hsp67Ba
      Drosophila melanogaster
      CG7409
      Drosophila melanogaster
      CG4461
      Drosophila melanogaster
      CG7409
      Drosophila melanogaster
      Hsp67Bc
      Drosophila melanogaster
      CG4461
      Drosophila melanogaster
      Hsp67Bc
      Homo sapiens
      CRYAA
      Homo sapiens
      CRYAB
      Homo sapiens
      CRYAB
      Homo sapiens
      102724652
      Homo sapiens
      HSPB6
      Homo sapiens
      102724652
      Homo sapiens
      HSPB6
      Homo sapiens
      CRYAA
      Mus musculus
      Hspb6
      Mus musculus
      Cryaa
      Mus musculus
      Cryaa
      Mus musculus
      Cryab
      Mus musculus
      Cryab
      Mus musculus
      Hspb6
      Rattus norvegicus
      Cryaa
      Rattus norvegicus
      Cryab
      Rattus norvegicus
      Cryab
      Rattus norvegicus
      Cryaa
      Rattus norvegicus
      Hspb6
      Rattus norvegicus
      Hspb6

      External links

      WormBase
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      Ensembl
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      Entrez Gene
      View on Entrez Gene database (179286)
      Homologues
      Search HomoloGene
      UniProt
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      Internet
      Search Google or Search Google Scholar