Caenorhabditis elegansGenAge entry for eif-3.F (Caenorhabditis elegans)

Gene information (ID: 218)

Symbol
eif-3.F
Name
Eukaryotic Initiation Factor
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Translation initiation factor (eIF) complex

Potential relevance to longevity and/or ageing

Observations
RNA interference in adulthood extended mean lifespan by 32%.
% change in avg or median lifespan
Average lifespan is 32% higher.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference
    Observations
    Post developmental RNAi resulted in a 28% mean lifespan extension.
    % change in avg or median lifespan
    Average lifespan is 28% higher.
    Lifespan Effect
    Increase
    Genetic Manipulation
    RNA interference
    Longevity Category
    Anti-Longevity
    Primary reference

      Homologs in other organisms

      Danio rerio
      eif3f
      Drosophila melanogaster
      CG9769
      Drosophila melanogaster
      CG8335
      Homo sapiens
      EIF3F
      Mus musculus
      Eif3f
      Rattus norvegicus
      Eif3f
      Saccharomyces cerevisiae
      RPN8
      Schizosaccharomyces pombe
      eif3f

      External links

      WormBase
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      Ensembl
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      Entrez Gene
      View on Entrez Gene database (174478)
      Homologues
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      UniProt
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      Internet
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