GenAge entry for egl-27 (Caenorhabditis elegans)
Gene information (ID: 1790)
- Symbol
- egl-27
- Name
- Protein EGL-27
- Organism
- Caenorhabditis elegans (AnAge)
Potential relevance to longevity and/or ageing
- Observations
- Overexpression of egl-27 extends the lifespan of wild-type animals. egl-27 is also required for longevity extension effects of impaired insulin/IGF-1 like signaling, as reduced egl-27 activity fully suppresses the longevity of daf-2 worms.
- % change in max lifespan
- Maximum lifespan is up to 10% higher.
- % change in avg or median lifespan
- Average lifespan is up to 17.9% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Overexpression
- Longevity Category
- Pro-Longevity
- Primary reference
-
Homologs in other organisms
No homologs found
External links
- WormBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (174121)
- Homologues
- Search HomoloGene
- UniProt
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- Internet
- Search Google or Search Google Scholar