GenAge entry for des-2 (Caenorhabditis elegans)
Gene information (ID: 175)
- Symbol
- des-2
- Name
- DEgeneration Suppressor
- Organism
- Caenorhabditis elegans (AnAge)
- Known functions and activities
- Alpha subunit of nicotinic acetylcholine receptor (nAChR)
Potential relevance to longevity and/or ageing
- Observations
- Mutations in both des(bs29) and des(bs30) increase lifespan by approximately 60%.
- % change in avg or median lifespan
- Lifespan is approximately 60% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Mutation
- Longevity Category
- Anti-Longevity
- Primary reference
-
Homologs in other organisms
- Danio rerio
- si:ch211-256e16.6
- Danio rerio
- si:ch211-256e16.4
- Danio rerio
- si:ch211-256e16.10
- Danio rerio
- si:ch211-256e16.7
- Danio rerio
- si:ch211-256e16.8
- Danio rerio
- htr3a
- Danio rerio
- htr3b
- Danio rerio
- si:dkey-49c17.4
- Danio rerio
- FO818743.1
- Danio rerio
- HTR3C
- Danio rerio
- CABZ01038483.1
- Drosophila melanogaster
- nAChRbeta3
- Homo sapiens
- HTR3D
- Homo sapiens
- HTR3A
- Homo sapiens
- ZACN
- Homo sapiens
- HTR3C
- Homo sapiens
- HTR3B
- Homo sapiens
- HTR3E
- Mus musculus
- Htr3b
- Mus musculus
- Htr3a
- Rattus norvegicus
- Htr3a
- Rattus norvegicus
- Htr3b
External links
- WormBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (179574)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar