GenAge entry for daf-7 (Caenorhabditis elegans)
Gene information (ID: 169)
- Symbol
- daf-7
- Name
- abnormal DAuer Formation
- Organism
- Caenorhabditis elegans (AnAge)
- Known functions and activities
- Encodes a member of the TGF-beta superfamily that affects dauer larvae
Potential relevance to longevity and/or ageing
- Observations
- Mutations cause up to 50% mean and maximum life-extension. This effect is dependent upon daf-3 and on daf-16 but independent of daf-2. RNA interference increased mean lifespan by 30% and maximum lifespan by 10%.
- % change in max lifespan
- Maximum lifespan is up to 50% higher.
- % change in avg or median lifespan
- Average lifespan is up to 50% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Mutation
- Longevity Category
- Anti-Longevity
- Primary reference
-
Homologs in other organisms
No homologs found
External links
- WormBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (175237)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar