Caenorhabditis elegansGenAge entry for daf-3 (Caenorhabditis elegans)

Gene information (ID: 165)

Symbol
daf-3
Name
abnormal DAuer Formation
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Transcriptional regulator

Potential relevance to longevity and/or ageing

Observations
Mutation in adults decreased mean lifespan by 6-16% and maximum lifespan by up to 30%.
% change in max lifespan
Maximum lifespan is up to 30% higher.
% change in avg or median lifespan
Average lifespan is 6-16% higher.
Lifespan Effect
Decrease
Genetic Manipulation
Mutation
Longevity Category
Anti-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    si:dkey-222b8.1
    Danio rerio
    SMAD4 (1 of many)
    Danio rerio
    si:dkey-239n17.4
    Danio rerio
    smad4a
    Drosophila melanogaster
    Med
    Homo sapiens
    SMAD4
    Mus musculus
    Smad4
    Rattus norvegicus
    Smad4

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (180431)
    Homologues
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    UniProt
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    Internet
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