Caenorhabditis elegansGenAge entry for cnb-1 (Caenorhabditis elegans)

Gene information (ID: 134)

Symbol
cnb-1
Name
CalciNeurin B
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Regulatory subunit of the protein phosphatase 2B that binds TAX-6 (a calcineurin A ortholog) in a calcium-dependent manner

Potential relevance to longevity and/or ageing

Observations
RNA interference increased mean lifespan by 30%.
% change in avg or median lifespan
Average lifespan is 30% higher.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    ppp3r1b
    Danio rerio
    ppp3r1a
    Drosophila melanogaster
    CanB2
    Drosophila melanogaster
    CanB
    Homo sapiens
    0
    Homo sapiens
    PPP3R2
    Homo sapiens
    PPP3R1
    Mus musculus
    Ppp3r1
    Mus musculus
    Ppp3r2
    Rattus norvegicus
    Ppp3r1
    Rattus norvegicus
    Rn50_14_1002.4
    Rattus norvegicus
    Ppp3r2
    Saccharomyces cerevisiae
    CNB1
    Schizosaccharomyces pombe
    cnb1

    External links

    WormBase
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    Entrez Gene
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    Homologues
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    UniProt
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    Internet
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