Caenorhabditis elegansGenAge entry for cgt-2 (Caenorhabditis elegans)

Gene information (ID: 1922)

Symbol
cgt-2
Name
Ceramide glucosyltransferase 2
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
RNA interference of CGT-2 (F20B4.6), a glucosylceramide synthase, results in both mean and maximum lifespan extension.
% change in max lifespan
Maximum lifespan is 24% higher.
% change in avg or median lifespan
Mean lifespan is 40% higher.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    ugcg
    Drosophila melanogaster
    GlcT-1
    Homo sapiens
    UGCG
    Mus musculus
    Ugcg
    Rattus norvegicus
    Ugcg

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (181790)
    Homologues
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    UniProt
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    Internet
    Search Google or Search Google Scholar