GenAge entry for cep-1 (Caenorhabditis elegans)
Gene information (ID: 116)
- Symbol
- cep-1
- Name
- C. Elegans P-53-like protein
- Organism
- Caenorhabditis elegans (AnAge)
- Known functions and activities
- Cell cycle control, apoptosis
Potential relevance to longevity and/or ageing
- Observations
- RNA interference increased mean lifespan up to 18% (dependent upon functional daf-16).
- % change in avg or median lifespan
- Average lifespan is 18% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- RNA interference
- Longevity Category
- Anti-Longevity
- Primary reference
-
- Observations
- Knockout mutants lived up to 33% longer (dependent upon functional daf-16).
- % change in avg or median lifespan
- Average lifespan is up to 33% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- Knockout
- Longevity Category
- Anti-Longevity
- Primary reference
-
- Observations
- RNAi resulted in a mean and maximal lifespan increased by 20% and 10% respectively.
- % change in max lifespan
- Maximum lifespan is 10% higher.
- % change in avg or median lifespan
- Average lifespan is 20% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- RNA interference
- Longevity Category
- Anti-Longevity
- Primary reference
-
Homologs in other organisms
No homologs found
External links
- WormBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (172616)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar