Caenorhabditis elegansGenAge entry for cel-1 (Caenorhabditis elegans)

Gene information (ID: 115)

Symbol
cel-1
Name
mRNA Capping Enzyme Like
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Possibly a mRNA capping enzyme

Potential relevance to longevity and/or ageing

Observations
RNA interference decreased median lifespan 76% in daf-2 mutants, 15% in daf-2/daf-16 double mutants, and 59% wild-type animals.
% change in avg or median lifespan
Median lifespan is 59% lower.
Lifespan Effect
Decrease
Genetic Manipulation
RNA interference
Longevity Category
Pro-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    rngtt
    Drosophila melanogaster
    mRNA-cap
    Homo sapiens
    RNGTT
    Mus musculus
    Rngtt
    Rattus norvegicus
    Rngtt
    Schizosaccharomyces pombe
    ceg1

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (172814)
    Homologues
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    UniProt
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    Internet
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