Caenorhabditis elegansGenAge entry for ceh-20 (Caenorhabditis elegans)

Gene information (ID: 1820)

Symbol
ceh-20
Name
Protein CEH-20
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
Several of the RNAi candidates (dve-1; lin-40; nhr-49; ceh-20; lin-11; and nhr-77) appeared to non-discriminately shorten lifespan in all strains tested, suggesting that the corresponding transcription factors are broadly required for survival. Interestingly, four RNAi clones (ZC123.3; nhr-119; ceh-37; and aha-1) affected wild-type and isp-1;ctb-1 mutant worms' lifespan to the same extent but exerted only a moderate or no effect on daf-16 and age-1 mutant longevity.
% change in avg or median lifespan
Average lifespan is 12% lower.
Lifespan Effect
Decrease
Genetic Manipulation
RNA interference
Longevity Category
Pro-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    pbx1a
    Danio rerio
    pbx2
    Danio rerio
    pbx4
    Danio rerio
    pbx3a
    Danio rerio
    CABZ01017151.1
    Danio rerio
    pbx3b
    Danio rerio
    pbx1b
    Drosophila melanogaster
    exd
    Homo sapiens
    PBX2
    Homo sapiens
    PBX1
    Homo sapiens
    PBX4
    Homo sapiens
    PBX3
    Mus musculus
    Pbx4
    Mus musculus
    Pbx1
    Mus musculus
    Pbx3
    Mus musculus
    Pbx2
    Rattus norvegicus
    Pbx1
    Rattus norvegicus
    AABR07021704.1
    Rattus norvegicus
    Pbx4
    Rattus norvegicus
    Pbx3
    Rattus norvegicus
    Pbx2

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (3565545)
    Homologues
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    UniProt
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    Internet
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