Caenorhabditis elegansGenAge entry for cco-2 (Caenorhabditis elegans)

Gene information (ID: 96)

Symbol
cco-2
Name
Cytochrome C Oxidase
Organism
Caenorhabditis elegans (AnAge)
Known functions and activities
Cytochrome c oxidase, subunit Va/COX6

Potential relevance to longevity and/or ageing

Observations
RNA interference results in a 53-57% increase in mean lifespan.
% change in avg or median lifespan
Average lifespan is 53-57% higher.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference
    Observations
    RNAi resulted in a 60% mean lifespan extension.
    % change in avg or median lifespan
    Average lifespan is 60% higher.
    Lifespan Effect
    Increase
    Genetic Manipulation
    RNA interference
    Longevity Category
    Anti-Longevity
    Primary reference

      In other databases

      GenAge microarray genes
      • A homolog of this gene for Homo sapiens is present as COX5A

      Homologs in other organisms

      Danio rerio
      cox5aa
      Danio rerio
      cox5ab
      Drosophila melanogaster
      CoVa
      Homo sapiens
      COX5A
      Mus musculus
      Cox5a
      Rattus norvegicus
      Cox5a
      Saccharomyces cerevisiae
      COX6
      Schizosaccharomyces pombe
      cox6

      External links

      WormBase
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      Ensembl
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      Entrez Gene
      View on Entrez Gene database (176707)
      Homologues
      Search HomoloGene
      UniProt
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      Internet
      Search Google or Search Google Scholar