Caenorhabditis elegansGenAge entry for cbs-1 (Caenorhabditis elegans)

Gene information (ID: 1973)

Symbol
cbs-1
Name
Cystathionine Beta-Synthase
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
Overexpression of CBS-1 significantly extended median lifespan of wild-type N2 controls by up to 50%, while maximal lifespan was mostly unaffected.
% change in avg or median lifespan
Median lifespan is approximately 50% higher.
Lifespan Effect
Increase
Genetic Manipulation
Overexpression
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Saccharomyces cerevisiae is present as CYS4
    GenDR gene manipulations
    • This gene is present as cbs-1

    Homologs in other organisms

    Saccharomyces cerevisiae
    CYS4

    External links

    WormBase
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (181215)
    Homologues
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    UniProt
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    Internet
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