- Symbol
- bcat-1
- Name
- Branched-chain-amino-acid aminotransferase, cytosolic
- Organism
- Caenorhabditis elegans (AnAge)
- Observations
- Downregulation of bcat-1 in worms increased mean lifespan by 25% and maximum lifespan by 19%. In addition to extending lifespan bcat-1 downregulation also increased health span.
- % change in max lifespan
- Maximum lifespan is 19% higher.
- % change in avg or median lifespan
- Mean lifespan is 25% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- RNA interference
- Longevity Category
- Anti-Longevity
- Primary reference
-
- Danio rerio
- bcat2
- Danio rerio
- bcat1
- Drosophila melanogaster
- CG1673
- Homo sapiens
- BCAT1
- Homo sapiens
- BCAT2
- Mus musculus
- Bcat2
- Mus musculus
- Bcat1
- Rattus norvegicus
- Bcat2
- Rattus norvegicus
- Bcat1
- Saccharomyces cerevisiae
- BAT1
- Saccharomyces cerevisiae
- BAT2
- WormBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (181423)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar