Caenorhabditis elegansGenAge entry for atad-3 (Caenorhabditis elegans)

Gene information (ID: 2012)

Symbol
atad-3
Name
ATPase family AAA domain-containing protein 3
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
RNA interference of mics-1 results in mutants with enhanced longevity when compated to HT115 wild-type controls (mean lifespan is 29% higher). Mutants are however highly sensitive to stress, displaying significantly higher levels of reactive oxygen species.
% change in avg or median lifespan
Mean lifespan is 29% higher.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference

    Homologs in other organisms

    Danio rerio
    atad3b
    Drosophila melanogaster
    bor
    Homo sapiens
    ATAD3B
    Homo sapiens
    ATAD3A
    Homo sapiens
    ATAD3C
    Mus musculus
    Atad3a
    Rattus norvegicus
    Atad3a

    External links

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    Entrez Gene
    View on Entrez Gene database (174590)
    Homologues
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    UniProt
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    Internet
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