- Symbol
- atad-3
- Name
- ATPase family AAA domain-containing protein 3
- Organism
- Caenorhabditis elegans (AnAge)
- Observations
- RNA interference of mics-1 results in mutants with enhanced longevity when compated to HT115 wild-type controls (mean lifespan is 29% higher). Mutants are however highly sensitive to stress, displaying significantly higher levels of reactive oxygen species.
- % change in avg or median lifespan
- Mean lifespan is 29% higher.
- Lifespan Effect
- Increase
- Genetic Manipulation
- RNA interference
- Longevity Category
- Anti-Longevity
- Primary reference
-
- Danio rerio
- atad3b
- Drosophila melanogaster
- bor
- Homo sapiens
- ATAD3B
- Homo sapiens
- ATAD3A
- Homo sapiens
- ATAD3C
- Mus musculus
- Atad3a
- Rattus norvegicus
- Atad3a
- WormBase
- Search
- Ensembl
- Search
- Entrez Gene
- View on Entrez Gene database (174590)
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar