Caenorhabditis elegansGenAge entry for ash-2 (Caenorhabditis elegans)

Gene information (ID: 892)

Symbol
ash-2
Name
ASH histone methyltransferase complex subunit (Drosophila absent, small or homeotic discs)
Organism
Caenorhabditis elegans (AnAge)

Potential relevance to longevity and/or ageing

Observations
30% mean lifespan extension
% change in avg or median lifespan
Average lifespan is 30% higher.
Lifespan Effect
Increase
Genetic Manipulation
RNA interference
Longevity Category
Anti-Longevity
Primary reference
    Observations
    Ash-2 deficiency in the parental generation extend the lifespan of descendants up until the third generation.
    % change in avg or median lifespan
    Lifespan is 19-27% higher.
    Lifespan Effect
    Increase
    Genetic Manipulation
    Mutation
    Longevity Category
    Anti-Longevity
    Primary reference

      Homologs in other organisms

      Danio rerio
      ash2l
      Drosophila melanogaster
      ash2
      Homo sapiens
      ASH2L
      Mus musculus
      Ash2l
      Rattus norvegicus
      Ash2l
      Schizosaccharomyces pombe
      ash2

      External links

      WormBase
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      Ensembl
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      Entrez Gene
      View on Entrez Gene database (174838)
      Homologues
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      UniProt
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      Internet
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