Mus musculusGenAge entry for Htr1b (Mus musculus)

Gene information (ID: 355)

Symbol
Htr1b
Name
5-hydroxytryptamine (serotonin) receptor 1B
Organism
Mus musculus (AnAge)
Known functions and activities
5-hydroxytryptamine (serotonin) receptor 1B

Potential relevance to longevity and/or ageing

Observations
Knockout mice displayed a decreased lifespan and early age-related motor decline.
Lifespan Effect
Decrease
Genetic Manipulation
Knockout
Longevity Category
Pro-Longevity
Primary reference

    In other databases

    GenAge model organism genes
    • A homolog of this gene for Caenorhabditis elegans is present as ser-4

    Homologs in other organisms

    Caenorhabditis elegans
    ser-4
    Danio rerio
    htr1b
    Drosophila melanogaster
    5-HT1B
    Drosophila melanogaster
    5-HT1A
    Homo sapiens
    HTR1B
    Rattus norvegicus
    Htr1b

    External links

    Mouse Genome Informatics
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    Ensembl
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    Entrez Gene
    View on Entrez Gene database (15551)
    Homologues
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    UniProt
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    Internet
    Search Google or Search Google Scholar